Systemic Treatment
Alprazolam (Xanax) may have an ameliorating effect. Systemic anticholinergics may be helpful, but unfortunately the dosages required to achieve reduced sweating also result in side effects including xerostomia, mydriasis, cycloplegia, and bowel and bladder dysfunction. Oxybutynin (Ditropan) has been found to be useful in episodic hyperhidrosis with hypothermia. Benztropine, was successfully used to treat hyperhidrosis in a patient with venlafaxine-induced excess sweating. Indomethacin, in a dose of 25 mg t.i.d. was effective for a patient with arthritis who coincidentally had lifelong idiopathic generalized hyperhidrosis. Clonidine has been found to be useful in the treatment of hyperhidrosis due to tricyclics or menopause.
Sarah J. Thompson, MD
Online Diagnosis of Symptoms and Medical Diseases Online Diagnosis of Psychiatric Disorders
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