Online Medical Diagnosis of Medical Problems and Symptoms - The National Medical Society





Postabsorptive hypoglycemia due to endogenous hyperinsulinism is often curable by the surgical removal of an insulinoma. If this is not possible because of multiple or metastatic tumors or the absence of a definable lesion, diazoxide is sometimes effective. Diazoxide (100 to 800 mg/d in adults and 5 to 30 mg/kg/d in infants) raises the plasma glucose concentration in large part by suppressing insulin secretion. Coadministration of a thiazide diuretic both limits sodium retention and potentiates the hyperglycemic action of diazoxide.

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Sarah J. Thompson, MD


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