Online Medical Diagnosis of Medical Problems and Symptoms - The National Medical Society


Diffuse, large B cell lymphoma, primary mediastinal lymphoma, anaplastic, large B cell lymphoma, anaplastic lymphoma of T and null cell types, peripheral T cell lymphoma, and mantle cell lymphoma


For patients with relapsed disease after initial CR with doxorubicin (Adriamycin), induction chemotherapy followed by ABMT is the current treatment of choice for those with IPI of 1 to 3; however, results for patients with IPI of 0 after standard salvage therapy are similar to those for patients undergoing ABMT. For patients with disease refractory to initial therapy, chemoinsensitive relapse, or those unable to undergo ABMT, remission can be induced with ifosfamide (Ifex), mitoxantrone (Novantrone), and cisplatin (Platinol-AQ) in various combinations. Promising agents in the salvage setting include paclitaxel (Taxol), docetaxel (Taxotere), topotecan (Hycamtin), and gemcitabine (Gemzar).


Sarah J. Thompson, MD


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