Cryptoglandular Infection
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The most common cause of anal fistula is cryptoglandular infection. Infections that begin in the anal glands can evolve and present as either abscesses or fistulas. Fistulas are common in patients with Crohn's disease. The track of anal fistulas can be extensive. The index of suspicion for Crohn's disease is increased by a history of episodes of diarrhea, abdominal cramping and weight loss, and the appearance, location and multiplicity of the fistulas.
Sarah J. Thompson, MD
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