Mohs' micrographic surgery involves gradual lesion excision using serial frozen section analysis and precise mapping of excised tissue until a tumor-free plane is reached. Mohs' micrographic surgery is used when tissue removal must be kept to a minimum for cosmetic reasons or to maximize function. It is the treatment of choice for difficult and high-risk squamous cell carcinomas, including lesions that are larger than 2 cm in diameter; located in areas where deep invasion is more likely or tumor extent is hard to assess, such as the nasolabial folds, eyelids and periauricular areas (facial "H zone"); rapidly growing; recurrent or incompletely excised; ill-defined; located in an area of previous irradiation; or located where perineural invasion is likely.
Sarah J. Thompson, MD
Online Diagnosis of Symptoms and Medical Diseases
Online Diagnosis of Psychiatric Disorders