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Endometrial PolipsEndometrial polips are benign tumors consisting of surface endometrium, fibrous stroma, and thick-walled, centrally positioned blood vessels. A clonal rearrangement of chromosome 6p21 is common in the mesenchymal (stroma) cells in the polip. endometrial polyps, endometrial hyperplasia The endometrial cells do not have the chromosome 6 rearrangement. One possible explanation of these findings is that an endometrial polip begins when a stromal cell undergoes a endometrial polyps, polyps, endometrial hyperplasia rearrangement in chromosome 6p21 resulting in an abnormal signal endometrial polyps, polyps, endometrial hyperplasia, polip to grow. The stromal elements proliferate and bring the endometrial glands Most endometrial polyps are solitary. In approximately 20% of cases endometrial polyps, polyps, endometrial hyperplasia multiple polyps are present. Polyps peak between ages 40 and 50 years, but many cases endometrial polyps, polyps, endometrial hyperplasia occur in menopausal women. In fewer than 1% of cases, polyps are associated endometrial polyps, polip with cancer. The usual presenting symptom is intermenstrual bleeding Polyps are typically diagnosed by sonography (especially sensitive in endometrial hyperplasia the follicular phase), saline infusion hysterosonography, hysterosalpingography, hysteroscopy, or curettage. Curettage often fails to remove endometrial polyps because of the mobility of their body and tip. In menopausal women taking hormone replacement therapy who have abnormal uterine bleeding, polyps are commonly found by hysteroscopy. Multiple case reports indicate that tamoxifen treatment may stimulate the development and growth of polyps, endometrial hyperplasia |