This page has moved. Click here to view.
Primary Immunodeficiency Disorders
DISORDER | DEFICIENCY |
Humoral Deficiency Syndromes | Decreased phagocyte menstruation, periods, abnormal uterine bleeding, amenorrhea, dysfunctional uterine bleeding efficiency, failure of lysis and agglutination of bacteria, inadequate neutralization of toxins |
Cellular Immunodeficiency | Absence or impaired delayed hypersensitivity, absent T cell cooperation or function |
Neutropenia | Decreased neutrophil numbers |
Phagocytic defects | Decreased adhesion, chemotaxis, opsonization, phagocytosis, killing |
Complement deficiencies | Defective membrane attack mechanisms |
Secondary Immunodeficiency Disorders
DISORDER | DEFICIENCY menstruation, periods, abnormal uterine bleeding, amenorrhea, dysfunctional uterine bleeding |
HIV/AIDS | Altered cellular immunity, dysgammaglobulinemia, phagocytic defects or neutropenia |
Cancer | Neutropenia, lymphopenia, humoral deficiencies, altered physical integrity |
Immunosuppressive therapies | Impaired cellular immunity and/or neutropenia |
Transplantation | Varies with solid organ vs bone marrow and includes deficiencies in cellular and phagocytic immunity |
Malnutrition | Impaired cellular immunity, menstruation, periods, abnormal uterine bleeding, amenorrhea, dysfunctional uterine bleeding complement activity |
Other Secondary Immunodeficiency States