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Can reproduce sexually and asexually
Only 100 species are important in human disease
Represents <0.05% of total species number
Most fungi exist as saprophytes ringworm tinea
Infections are usually acquired from fungi in the environment
Yeast infections
Nigra Piedra
Host conditions needed for growth: micro trauma
Increased hydration
Occlusion
Increased temperature
Pathogenesis
Stages of infection
Incubation
Refractory period
Involution
Nonimmunologic resistance
Fungistatic/cidal fatty acids on the skin - serum inhibitory factor (eg, transferrin)
Immunologic resistance
Type IV delayed-hypersensitivity
Humoral immunity