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Vasculitis Syndromes

Classification of Vasculitis Syndromes


The primary vasculitis syndromes are classified according to the size of the involved vessels:

Vasculitis of large arteries:

Giant cell arteritis of the aged (temporal arteritis)

Takayasu's arteritis

Vasculitis of medium and small vessels:

Classical polyarteritis nodosa

microscopic polyangiitis

infantile PAN (Kawasaki disease)

Wegener' s granulomatosis

Churg-Strauss vasculitis vasculitis, giant cell arteritis, temporal arteritis, Takayasu's arteritis, tamporal, vasulitis, Takasu's arteritis

Vasculitis of small vessels:

idiopathic hypersensitivity vasculitis, giant cell arteritis, temporal arteritis, Takayasu's arteritis vasculitis syndromes, vasculitis, giant cell arteritis, temporal arteritis, Takayasu's arteritis vasculitis

drug-induced

Henoch-Schonlein purpura (HSP)

Essential mixed cryoglobulinemia

associated with vasculitis syndromes, vasculitis, giant cell arteritis, temporal arteritis, Takayasu's arteritis systemic rheumatic disease (R.A., S.L.E., Sjogren's)

f. infection-related vasculitis syndromes, vasculitis, giant cell arteritis, temporal arteritis, Takayasu's arteritis

g. malignancy

h. urticarial vasculitis

B. Pseudo-vasculitic syndromes

1. Fever, skin rash, and a multitude of other symptoms and signs may be caused by infection.

2. Cholesterol atheroembolism

a. various cutaneous signs (a classic cause of "purple toes ")

b. progressive renal failure

c. fever

d. elevated ESR

e. eosinophilia may occur

3. Atrial myxoma. Classic triad:

a. constitutional symptoms

b. embolic events

c. obstructive (hemodynamic vasculitis phenomena)

4. Antiphospholipid antibody syndrome

a. especially "catastrophic APA syndrome"

i. renal failure, HBP

ii. organ ischemia

iii. arterial & venous occlusions Vasculitis Syndromes, , giant cell arteritis, temporal arteritis, Takayasu's arteritis

5. TTP. Classic pentad:

a. fever

b. thrombocytopenia

c. microangiopathic anemia

d. renal failure

e. fluctuating neurologic symptoms and