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Anti-fungal Therapy

Spectrum of Anti-fungal Agents

Class	Superficial	Cutaneous	Systemic
Antifungals Antifungals	Topicals	XXX	-	-
Antifungals	Griseofulvin	XXX		-
Azoles Ketoconazole Fluconazole Itraconazole antifungals, anti-fungal	XXX	XXX	XXX
Polyenes Nystatin	XXX	-	-
Amphotericin B	-	XXX	XXX

  Topical Antifungal Agents

Agent	Ringworm	T. versicolor	Candidiasis
Naftifine	XXX	XXX	XXX
Clotrimazole	XXX	XXX	XXX
Nystatin	-	-

Topical Anti-fungal Agents

CLASS

· Naftifine - allylamine derivative

· Clotrimazole - imidazole

· Nystatin - polyene

_ METABOLISM

· Naftifine renal

· Clotrimazole - hepatic