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Clinical Aspects of Hematopoiesis

Overview of Hematopoietic Cell Growth and Differentiation

Pluripotential stem cells

Progenitor cells committed to specific cell lineages

Precursor cells recognizable in the bone marrow

Circulating RBCs, WBCs, platelets

The Important Hematopoietic Factors and Their Biologic Functions

Several growth factors act cooperatively at each of the different stages of hematopoietic cell development. Some growth factors (eg, stem cell factor (SCF) and IL-3), hematopoiesis, anemia tend to act at earlier stages and on multiple cell lineages; others, like erythropoietin and thrombopoietin, act on later, more

Major Hematopoietic Growth Factors

Diseases of Hematopoietic Stem Cells and Progenitor Cells

Diseases: Hematopoiesis