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Pathology of Ovary and Ovarian Neoplasms

CLASSIFICATION OF OVARIAN NEOPLASMS: TUMORS

Surface epithelial

Sex-cord stromal

Steroid (lipid) cell

Germ cell

Mixed germ cell: sex-cord stromal

Miscellaneous and metastatic/secondary

While ovarian tumors demonstrate tremendous histological diversity, there is considerable overlap in their gross appearance making their distinction often difficult on gross examination alone.

A variety of clinicopathologic data are important to help narrow the diagnostic choices.

Age of the patient

(1) If < 50, only approximately 13% are malignant

(2) If > 50, approximately 45--50% malignant

(3) Dermoid cysts and sex-cord stromal tumors occur at all ovary cancer ages

(4) Malignant germ cell tumors almost always occur in those younger than age 50

b. Bilateral or unilateral tumor

1) Sex-cord stromal tumors are almost always unilateral and

confined to the ovary

(2) Metastatic tumors are bilateral 65 % of the time

SURFACE EPITHELIAL TUMORS

General information

Account for two-t & of all ovarian neoplasms

Treatment